INSTAMOISTSHIELD is cellulose based, fully formulated, high-performance dry powder film coating system for use with organic or hydro-alcoholic solvent systems. It can be used as a basic film coating system in its own right or as a protective seal coat prior to further processing. It is suitable for all types of coating equipment.
75% IPA + 25% Purified Water at up to 9% solids
35% IPA + 65% MDC at up to 5% solids
Variable-speed mechanical stirrer
Mixing Vessel
Instamoistshield (Organic): Determine the quantities of Instamoistshield (5% w/w solids) and 35% IPA + 65% MDC required, based on the quantity of tablets to be coated and the target coating weight gain. e.g.: For coating 1.0 kg of tablets to 3% wt. gain, weigh 33 g Instacoat and 627 gm 35% IPA + 65% MDC at room temperature (includes 10% overage for losses).
Instamoistshield (Hydro-alcoholic): Determine the quantities of Instamoistshield (9% w/w solids) and 75% IPA + 25% Purified Water required, based on the quantity of tablets to be coated and the target coating weight gain. e.g.: For coating 1.0 kg of tablets to 3% wt. gain, weigh 33 gm Instacoat and 334 gm 75% IPA + 25% Purified Water at room temperature (includes 10% overage for losses).
Instamoistshield (Organic or Hydro-alcoholic): Add the weighed quantity of solvent to a mixing vessel.
Using a mechanical stirrer, stir the solvent to form a vortex.
Add the required quantity of Instamoistshield to the centre of the liquid vortex in a slow steady stream, avoiding clumping while maintaining a vortex. Once the entire quantity of powder has been added, reduce the stirrer speed to eliminate the vortex. (Fig. 2) Continue mixing for 45 minutes.
Side-vented (fully perforated) pans | Conventional (non perforated) pans | |
---|---|---|
Pan diameter (inch) | 24-60 | 12-36 |
Tablet load (kg) | 10-300 | 0.5-50 |
Weight gain (%) | 3.5-4.0% | |
Number of guns | 1-6 | 1 |
Liquid nozzle diameter (mm) | 1.0-1.2 | |
Atomising air pressure (bar) | 2.5-3.0 | |
Pattern air pressure | To achieve maximum uniform bed coverage | |
Tablet bed temperature (⁰C) | 36-38 | |
Tablet bed temperature, Hydro-alcoholic (⁰C) | 36-38 | |
Tablet bed temperature, Hydro-alcoholic (⁰C) | 38-40 | |
Tablet bed temperature, Hydro-alcoholic (⁰C) | 38-40 | |
Inlet air temperature (⁰C) | Set to achieve required product bed temperature | |
Suspension spray rate | Set to achieve required product bed temperature | |
Exhaust air volume | To maintain slight negative pressure in pan | |
Pan speed | Minimum for steady tablet flow through spray zone |
*Tablet bed temperature offers the most effective way of controlling the coating process. Where this measurement is unavailable, exhaust temperature may be substituted. However, the relationship between the two measurements is complex and depends on several factors such as pan load, pan depression, pan design and airflow rate. Indicated exhaust temperature may be above or below the true bed temperature. It is recommended that the relationship between the two measurements is calibrated.
Cellulosic Polymers; Plasticiser; Titanium Dioxide; Edible Pigments, Glidant.