INSTACOATTM Natcol is a unique film coating system consisting of a dry blend of polymers, plasticizers, pigments, opacifiers and other excipients. Its uniqueness lies in the selection of natural colorants. The system is optimized and validated to offer complete film coating solution and enhancing organoleptic appeal. This is ultimately translated into better patient compliance providing unique product identification.
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INSTACOAT NATCOL | |
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All products are checked for the regulatory compliance of all ingredients in the target countries and market segments of sale. This determination is made at the time the initial formulation is established, based on customer-supplied information. If market countries and/or segments are extended once the formulation has been established, customers are encouraged to contact us to ensure that regulatory compliance is not compromised.
These factors will all depend on the polymer base that has been chosen. Please refer to the process guidance sheet supplied with the original sample from our laboratories or contact us for this information.
Variable-speed mechanical stirrer
Mixing Vessel
Add the weighed quantity of the chosen solvent to a mixing vessel.
Using a mechanical stirrer, stir the solvent to form a vortex.
Add required quantity of Instacoat to the centre of the liquid vortex in a slow steady stream, avoiding clumping, while maintaining a vortex. Once the entire quantity of Instacoat has been added, reduce the stirrer speed to eliminate the vortex. (Fig. 2) Continue mixing for 45 minutes.
NOTE: With some mixed solvent systems the Instacoat is dispersed in one solvent before addition of the other solvent. Please refer to the guidance mentioned above for details.