Espheres SiO2

Espheres SiO2

ESPHERES SiO2 (Colloidal Silicon Dioxide Spheres)

Colloidal Silicon Dioxide (SiO2) spheres are hard free flowing spherical masses prepared principally using Colloidal Silicon Dioxide plus some minor common excipients required for making spheres.

The ingredients used have GRAS status and are compliant with monographs of all the recognized pharmacopoeias.

Important Features of Espheres SiO2

  • Uniform sphere size

  • Low friability

  • Insoluble in water

  • Uniform and consistent loading

  • Cost effective

  • Availability in various size range

General Physico-chemical Characteristics

  • Appearance
  • White hard free flowing spherical pellets
  • Loss on Drying
  • Not more than 10% w/w
  • pH
  • 5 to 7.5 (2% aqueous dispersion)
  • Solubility
  • Insoluble in water
  • Microbial Enumeration Test
  • Complies with pharmacopoeial requirements
  • Pathogens
  • Absent

Storage conditions

Protect from excessive temperature moisture and freezing.

Re-evaluation Date - 36 months from the date of manufacture.

Application

These spheres can be used as an inert base for modified release formulations promoting consistency and uniformity of release profile thus ensuring a uniform therapeutic response.

Particle Sizes (U.S. Standard Sieve) Available

#30 – #40 and #40 - #60

  • Size considerations - Not less than 90% pass through the coarser sieve size and not more than 10% passes the finer sieve. These sizes are stated on the label.

For more details about ESPHERES™ products, please contact us at info@idealcures.co.in